Toxic Epidermal Necrolysis Occurring in a Child
نویسندگان
چکیده
منابع مشابه
Severe Antiretroviral Therapy-Induced Toxic Epidermal Necrolysis in a Child
Toxic epidermal necrolysis (TEN) is a rare and life-threatening condition characterised by extensive epidermal detachment and mucosal erosion. Adverse drug reaction is a strongly correlated causative factor and TEN is currently considered the most severe end of a spectrum of drug-induced mucocutaneous diseases, including Stevens-Johnson syndrome. Attaining an accurate and detailed patient histo...
متن کاملToxic epidermal necrolysis induced by lamotrigine treatment in a child
Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis. This condition is triggered by many factors, principally drugs such as antiepileptic medications, antibiotics (particularly sulfonamide), nonsteroidal anti-inflammatory drugs, allopurinol, and nevirapine. Lamotrigine has ...
متن کاملToxic epidermal necrolysis occurring during treatment with trimethoprim alone.
Case I-A 56 year old man with mild hypertension sustained a cerebrovascular event in 1980 after which he had a mild right facial weakness and mild right hemiparesis. In 1981 he presented to this clinic with shooting pains affecting the right side of his body. He was successfully treated with sodium valproate and amitriptyline for three years. In 1984 the pain recurred and was worse and he also ...
متن کامل[Toxic epidermal necrolysis].
Toxic epidermal necrolysis is a potentially fatal dermatological disease. Large bullae covering extensive areas of the body cause continuous exfoliation of skin, which requires immediate medical attention. Intraoral manifestations may precede cutaneous lesions. Two cases with different treatment protocols are presented.
متن کاملToxic Epidermal Necrolysis
Figure 1. Generalized epidermolysis on anterior and posterior torso with crusty erosions on oral mucosa. DESCRIPTION A 33-year-old woman presents with diffuse rash 3 weeks after completing a course of Bactrim for a urinary tract infection. Erythematous maculopapular rash is evident on the trunk and extremities with painful, epidermal sloughing on the back leaving a moist, denuded dermis. Note t...
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ژورنال
عنوان ژورنال: BMJ
سال: 1959
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5151.544